Food and drugs…watch out for any interactions

Antibiotics are best when taken on an empty stomach, or one that is full? Laxatives prior to or after meals? with cold or hot drinks? Certain drugs are affected by interactions with specific kinds of food or drinks However, we often don’t know about the possibility, or underestimate the situation. Better to learn more about the issue and follow simple but efficient guidance.

“Just one teaspoon in sugar” and the pills will go down …”, as does an iconic tune that’s the soundtrack of the one of most well-known films that is loved by children and oldalike “Mary Poppins”. However, in the aftermath of this hit song Have we ever asked ourselves whether taking pills with a particular kind of drink or food at a particular moment, rather than other times, is completely unimportant. In some instances we’ve reported the matter to a physician or rely on the information provided on the leaflet for the medication which is, unfortunately, not always complete and there are many instances when we’ve not asked the question. We often encounter ourselves taking medications that range from the most basic and occasionally to more specific ones that last longer and without paying much focus on what we eat and with the type of food with which we include them with, whether it’s best to consume it when we are not hungry or with an empty stomach, or whether it’s better to consume it prior to or following meals. A collection of basic and everyday facts that are important to understand in order to ensure that the effectiveness of a substance diminished and to avoid unpleasant reactions and to reduce adverse consequences. Without causing unnecessary anxiety and causing unnecessary anxiety, the negative interactions that can happen between drugs and food shouldn’t be overlooked. Thus, the expression “if you are aware of it is there, stay clear of it!” is still true.

Liquids or solids?

Naturally, it is not wise to make generalizations because not all medications have this kind of interaction. In general, foods that are solid can slow the process of emptying the gastric tract and reduce the absorption speed of certain medications. Liquids, on one on the other hand, speed up the digestion process and reduce the time between the consumption of the medication and the manifestation in its effect. Most interactions happen in the process of metabolism of drugs based depending on the speed and the substance however, they also impact its metabolism, on its elimination, and on therapeutic effect that could be lowered or increased.

If you’re eating well, what happens?

Alongside the type of drug, it is equally important the amount of food consumed when taking the drug. While in certain situations it is safe to take them with unfulfilled stomachs, but in others it is essential that the drug is taken together with food to avoid irritation of the gastric mucosa , or to increase their absorption such as the so-called NSAIDs (non steroidal anti-inflammatory medications). If the drug is to be taken with an empty stomach, it’s best to pair it with lighter and protein-rich meals whose digestion, in addition to causes an increase in gastric juices, which aid in breaking down of drug. The more a meal is nourishing and rich in fats the longer the period of absorption is extended which delays the entry to the drugs into circulation.


Grapefruit’s undesirable effects are not pleasant.

There are increasingly research studies into possible interactions between grapefruit, and in particular its juice, and certain forms of drugs. Researchers have discovered in the fruit a few compounds, including furocoumarins, as well as a bioflavonoid called Naringin that in combination with a drug for generating concentrations in blood of the substance which are 3-8 times greater than what is normal. A glass of juice is sufficient and it can happen even 24 hours after the time of consumption. This is why it should be avoided by those who take antidepressants, anxiolytics and antihistamines, calcium channel blockers (for heart problems) anti-inflammatory drugs (after transplants) and statins (for the treatment of heart diseases) as well as some anti-inflammatory medicines (corticosteroids).


Medicines to drink

Another important thing to think about is the fluids you drink when you are taking your various medicines.

Water is the best liquid. Best at room temperature. Drinks that are cold speed up the rate of gastric transit. However, hot drinks however can reduce it.

Alkaline waters – The minerals in these waters can interact with certain types of antibiotics , and could decrease their effectiveness.

Milk should not be attributed, as with all dairy products generally with antibiotics (in particular tetracyclines , quinolones and tetracycl) due to the calcium content that influences its metabolism.

Acid drinks and fruit juices (tomato juice smoothies, juices …) These drinks can cause gastric issues, and are especially by taking penicillins.

Grapefruit juice can increase the effectiveness of many medications by 3 to 8 times

In comparison to the normal

Caffeinated drinks (tea coffee, tea, cola and cocoa) due to their stimulating effects they are in opposition to the purpose of drugs against arterial hypertension as well as the ones that already contain caffeine (some anti-influenza and anti-inflammatory medications).

Alcohol – Complete prohibition as our common sense would recommend, for everything however, it is particularly relevant to sleeping medications or Antidepressants (tricyclics as well as benzodiazepines) along with aspirin (possible intestinal bleeding) and paracetamol-based antifluenza drugs and antihistamines from the past generation.


The rules of “pi the llole”

Antibiotics-antibacterials – In most cases ( particularly tetracyclines) 1 hour before or 2 hours after meals.

Erythromycin – . Avoid dairy products, drinks or food items that contain caffeine.

Anti-inflammatory drugs and pain relievers – immediately after meals to prevent gastric issues. Antispasmodics with alkaline are recommended for 2 hours following eating.

Antiallergens – 1 hour prior to meals.

Antihistamines before bedtime, and a minimum of 1 hour prior to meals.

Cardiotonics: 1 hour prior to meals.

Oral contraceptives – Right after meals.

Diuretics are recommended for use during meals. avoid eating foods that are high in sodium and potassium (bananas or oranges, as well as the salt-replacement products).

Thyroid medicines

The best time to take thyroid medications is in the morning, 30-60 minutes. prior to breakfast.

Osteoporosis (hormone-based) treatments – On getting up, about an hour before breakfast.

Anti-cholesterol and triglyceride medicines immediately following dinner avoid the consumption of alcohol and foods high in fiber whenever possible.

Laxatives are generally taken upon awakening Most before bedtime.

Sedatives, antidepressants . The strongest are best taken prior to going to bed, and the other ones one hour prior to main meals. Avoid eating foods high in vitamin B12 simultaneously such as shellfish, offal and Brewer’s yeast. If you are taking antidepressants, steer clear of aged cheeses.

The milk’s enzymes as well as vitamins immediately prior to meals.



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